AZD 4407 (ZD 4407) (Synonyms: ZD 4407) |
| Catalog No.GC32035 |
AZD 4407 (ZD 4407) is a potent 5-lipoxygenase inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 166882-70-8
Sample solution is provided at 25 µL, 10mM.
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AZD 4407 is a potent 5-lipoxygenase inhibitor.
In view of the powerful spasmogenic actions of leukotrienes in vascular and bronchial tissue, drugs which block their biosynthesis by inhibiting 5-lipoxygenase may have therapeutic potential in a variety of inflammatory conditions including inflammatory arthropothies, asthma, psoriasis, and inflammatory bowel disease. One such compound is AZD 4407 (ZD4407)[1].
[1]. Jonathan Hutton, et al. Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407. Org Process Res Dev. 1997 Jan 15;1(1): 61-67.
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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