|Azetidine-2-carboxylic acid Catalog No.GC33415|
Sample solution is provided at 25 µL, 10mM.
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|Cas No.||2517-04-6||SDF||Download SDF|
|Solubility||H2O : 50 mg/mL (494.56 mM)||Storage||Store at -20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent.
Azetidine-2-carboxylic acid (375-5oo μg per day) is incorporated into the collagen synthesized by chick embryo cartilage in vitro.
. Rubenstein E, et al. Azetidine-2-carboxylic acid in the food chain. Phytochemistry. 2009 Jan;70(1):100-4. . Rubenstein E, et al. Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. J Neuropathol Exp Neurol. 2008 Nov;67(11):1035-40. . Lane JM, et al. Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. I. Arrest of collagen accumulation in growing chick embryos. Biochim Biophys Acta. 1971 Jun 29;236(3):517-27.