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Banoxantrone D12 (AQ4N D12) (Synonyms: AQ4N D12)

Catalog No.GC33240

Banoxantrone D12 (AQ4N D12) is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

Banoxantrone D12 (AQ4N D12) Chemical Structure

Cas No.: 1562067-05-3

Size Price Stock Qty
1mg
$321.00
In stock
5mg
$1,011.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Product Documents

Quality Control & SDS

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Background

Banoxantrone D12 (AQ4N D12) is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

Chemical Properties

Cas No. 1562067-05-3 SDF
Synonyms AQ4N D12
Canonical SMILES O=N(C([2H])([2H])[2H])(C([2H])([2H])[2H])CCNC1=CC=C(NCCN(C([2H])([2H])[2H])(C([2H])([2H])[2H])=O)C(C(C2=C(O)C=CC(O)=C23)=O)=C1C3=O
Formula C22H16D12N4O6 M.Wt 456.55
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.1903 mL 10.9517 mL 21.9034 mL
5 mM 0.4381 mL 2.1903 mL 4.3807 mL
10 mM 0.219 mL 1.0952 mL 2.1903 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

Review for Banoxantrone D12 (AQ4N D12)

Average Rating: 5 ★★★★★ (Based on Reviews and 27 reference(s) in Google Scholar.)

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