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Beaucage reagent

Catalog No.GC32333

Beaucage reagent is found to be potent in causing DNA cleavage.

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Beaucage reagent Chemical Structure

Cas No.: 66304-01-6

Size Price Stock Qty
10mM (in 1mL DMSO)
$50.00
In stock
250mg
$46.00
In stock
1g
$91.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Beaucage reagent is found to be potent in causing DNA cleavage.

[1]. Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent. Org Biomol Chem. 2010 Mar 21;8(6):1293-5.

Chemical Properties

Cas No. 66304-01-6 SDF
Canonical SMILES O=C(C1=CC=CC=C12)SS2(=O)=O
Formula C7H4O3S2 M.Wt 200.23
Solubility DMSO : ≥ 100 mg/mL (499.43 mM);Water : < 0.1 mg/mL (insoluble) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 4.9943 mL 24.9713 mL 49.9426 mL
5 mM 0.9989 mL 4.9943 mL 9.9885 mL
10 mM 0.4994 mL 2.4971 mL 4.9943 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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