Home>>Signaling Pathways>> PI3K>> PI3K/Akt/mTOR Signaling>>BEBT-908 (PI3Kα inhibitor 1)
BEBT-908 (PI3Kα inhibitor 1) Catalog No.GC33145

Size Price Stock Qty
10mM*1mLinDMSO
$359.00
In stock
5mg
$321.00
In stock
10mg
$459.00
In stock
50mg
$1,379.00
In stock
100mg
$1,930.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 1235449-52-1 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES CN(CC1=CC(N=C(C2=CN=C(NC)C=C2)N=C3N4CCOCC4)=C3S1)C5=NC=C(C(NO)=O)C=N5
Formula C23H25N9O3S M.Wt 507.57
Solubility DMSO : ≥ 37 mg/mL (72.90 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

BEBT-908 is a selective PI3Kα inhibitor extracted from patent US/20120088764A1, Compound 243, has an IC50<0.1 μM, PI3Kα inhibitor 1 also inhibits HDAC (0.1 μM≤IC50≤1 μM) .

[1]. Cai Xiong, et al. Deazapurines, thienopyrimidines and furopyrimidines as phosphoinositide 3-kinase inhibitors with a zinc binding moiety and their preparation and use in the treatment of diseases. From U.S. Pat. Appl. Publ. (2012), US 20120088764 A1 20120412.