BI 9321 |
| Catalog No.GC50540 |
Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain
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Cas No.: 2387510-86-1
Sample solution is provided at 25 µL, 10mM.
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Nuclear receptor-binding SET domain (NSD) 3 antagonist (IC50 = 1.2 μM). Selectively binds the PWWP1 domain of NSD3 (Kd = 166 nM). Antagonizes the interaction of H3 with NSD3-PWWP1 in U2OS cells.
Böttcher et al (2019) Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol. 15 822 PMID:31285596
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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