BIX NHE1 inhibitor |
| Catalog No.GC50659 |
BIX NHE1 inhibitor is potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC50s of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1422252-46-7
Sample solution is provided at 25 µL, 10mM.
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Potent and selective NHE1 inhibitor (IC50 = 31 nM). Selective for NHE1 over NHE2 and NHE3. Prevents ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo. Prevents phenylephrine-induced cardiomyocyte hypertrophy in vitro, and attenuates cardiac hypertrophy and left ventricular dysfunction postinfarction in rats. Orally bioavailable.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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