bk-2C-B (hydrochloride) (Synonyms: bk-4-Bromo-2,5-dimethoxyphenethylamine) |
| Catalog No.GC42945 |
A series of 2,5-dimethoxyphenethylamines, substituted at the four position of the aromatic ring, have psychoactive effects.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2303508-66-7
Sample solution is provided at 25 µL, 10mM.
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A series of 2,5-dimethoxyphenethylamines, substituted at the four position of the aromatic ring, have psychoactive effects. [1][2] 2C-B (hydrochloride) is a hallucinogenic designer drug that activates the serotonin receptor 5-HT2C (pEC50 = 6.8 for arachidonic acid release) and has emerged as a drug of abuse.[1][2][3] bk-2C-B is a β-ketone analog of 2C-B.[4] This product is intended for forensic and research purposes.
Reference:
[1]. Bruno, R., Matthews, A.J., Dunn, M., et al. Emerging psychoactive substance use among regular ecstasy users in Australia. Drug Alcohol Depend. 124(1-2), 19-25 (2012).
[2]. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. Journal of Pharmacology and Experimental Therapeutics 321, 1054-1061 (2007).
[3]. Maurer, H.H. Chemistry, pharmacology, and metabolism of emerging drugs of abuse. Therapeutic Drug Monitoring 32(5), 544-549 (2010).
[4]. Westphal, F., Junge, T., Girreser, U., et al. Structure elucidation of a new designer benzylpiperazine: 4-Bromo-2,5-dimethoxybenzylpiperazine. Forensic Science International 187(1-3), 87-96 (2009).
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