CEPT Cocktail
CEPT, the combination of Chroman 1, Emricasan, a Polyamine solution, and Trans-ISRIB, has been found to secure several applications in research, regenerative medicine, cell therapy, cryobiology, and drug development to enhance the viability and expansion of human pluripotent stem cells in culture or to upgrade the functionality of multiple derived cell types.
Blasticidin S HCL
Blasticidin S HCL being a nucleoside analogue antibiotic, exhibits broad-spectrum efficacy against eukaryotic and prokaryotic cells. Isolated from Streptomyces griseochromogenes. Blasticidin S serves as the selection agent while demonstrating many antiviral, anti-tumor, and antifungal properties way beyond its antimicrobial activity.
GW9662
GW9662 exhibits half maximal inhibitory concentration (IC50) of 3.3 nM and is a well-characterized inhibitor of peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating high selectivity for PPARy with the inhibitory activity greater for PPARγ about 10 to 600 times compared to PPARα and PPARδ in cellular environments.
Deferoxamine Mesylate
In the vast expanse of medical science, where each discovery is a step towards unraveling the mysteries of human health, Deferoxamine Mesylate emerges as a pivotal breakthrough in the realm of iron chelation therapy.
Brefeldin A
Cytotoxin Produced by diverse kinds of fungi e.g Paecilomyces sp. And Aspergillus clavatus isolated from Taxus mairei and Torreya grandis from Southeast china, 12,15-Dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one also called as Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor.
Mdivi 1
Mitochondrial division inhibitor-1 (Mdivi-1) ( mol.weight : 353.22, empirical formula: C15H10Cl2N2O2S) is a small chemical inhibitor of mitochondrial division dynamin, which plays multiple roles in mitochondrial dynamics, mitochondrial autophagy, ATP production, the immune response, and Ca²⁺ homeostasis.
RIPA Lysis Buffer (Strong)
RIPA Lysis Buffer is a traditional rapid lysis buffer for cellular tissues. It is a lysis and washing buffer that is used in reporter gene detection, protein kinase experiments, immunoassays, and protein purification.
BODIPY 493/503
BODIPY 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-SIndacene) usually employed for the quantification of neutral lipid content by utilizing flow cytometry and for the observation of lipid droplets by microscopy, is a fluorescent and a neutral lipid.
12-o-tetradecanoylphorbol-13-acetate (TPA, PMA)
Within the field of normal disquisition, certain mixes play a critical portion in unleashing the bigwig data of cellular forms and understanding complex common fabrics. Chemical mixes have continuously charmed experimenters with their one of a kind packages and empirical operations.
Cycloheximide
Produced by the bacterium Streptomyces griseus, Cycloheximide is a glutarimide antibiotic, occupying a unique space in the scientific tool box due to its antifungal properties and potential role in the inhibition of protein synthesis.