LX1032, LX1606, LX1606 Hippurate and are the various names used in scientific literature for the Telotristat Etiprate (TE). It is a small and new molecule. Its molecular structure is diagrammatically depicted in Figure 1.

CP-456773, cytokine release inhibitory drug-3 CRID3, MCC950 sodium and MCC950, all are the short forms for N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide. Chemically, it is a derivative of diaryl sulfonylurea derivative. It is a small molecule. Its molecular structure is diagrammatically depicted in Figure 1. The roadmap for its synthesis is documented in the scientific literature in detail.

BMPO, BocMPO or 5-BMPO cpd is the short form available for 5-tert-butoxycarbonyl 5-methyl-1-pyrroline N-oxide. It is novel spin trap, which is butoxylated. It molecular structure is diagrammatically depicted in Figure 1. The detailed protocol for its synthesis has already been documented in the scientific literature

H2DCFDA or DCFH-DA is the short form, which is used for 2',7'-dichlorodihydrofluorescein diacetate. Its molecular structure is diagrammatically depicted in Figure 1. It is neutral as it does not carry a net electric charge, thus it is non polar also.

Mitomycin C is also known as 7-amino-9α-methoxymitosane (Carlos de Oliveira and Wilson, 2020). Chemically, Mitomycin C is a small molecule. Its molecular structure is diagrammatically shown in Figure 1.

Chemically, GW 4869 is a small and novel molecule highly specific in its inhibitory action. Its molecular structure is diagrammatically depicted in Figure 1. It is cationic and also hydrophobic in its behavior. GW 4869 inhibits sphingomyelinases (SMase), more specifically neutral sphingomyelinase 2 (N-SMase 2), also termed sphingomyelin phosphodiesterase 3 (SMPD3) (Vuckovic et al., 2017) in a non-competitive and Magnesium ion dependent manner under both conditions, i.e., in vitro and in vivo, with the half-maximal inhibitory concentration (IC 50) of 1 micro-Molar (μM). This inhibition is tissue dependent as GW 4869 does not inhibit neutral sphingomyelinase 2 (N-SMase 2) in the Multiple myeloma (MM) cells (Vuckovic et al., 2017). SMase is a hydrolase thus, when active it catalyzes the hydrolysis of Sphingomyelin that results in the production of phosphorylcholine and lipid ceramide, that is bioactive in nature. As this hydrolysis occurs optimally at the pH value 7, thus these SMases are termed as neutral sphingomyelinase (N-SMase) (Canals et al., 2011).