Compound library

What’s Compound Library

A compound library, also known as a Compound Library, is a collection of entities or information composed of multiple small molecule compounds according to certain requirements (such as specific structures or functions). The Compound Library contains information such as molecular structure, physicochemical properties, and relevant experimental data. Researchers can use the compound library for high-throughput screening, high content screening, molecular design, drug discovery, molecular docking, and other operations to quickly screen compounds with potential pharmacological effects. Compound libraries can be used in fields such as cancer, inflammation, virology, biomedicine, medicinal chemistry, and chemical biology.

Applications of Molecular Libraries in Drug Development

1. Drug screening: Molecular libraries are important tools for drug screening, helping scientists find promising compounds for new drug development or implementers of specific cellular functions. Through high-throughput screening (HTS) and high content screening (HCS), molecular libraries can quickly identify compounds with potential pharmacological effects

2. Drug design: Biological activity data and physicochemical property data in molecular libraries are crucial for compound screening and drug design. Researchers can use this data to predict the biological activity of compounds, thereby screening potential drug candidates

3. Molecular docking and virtual screening: The Compound Library supports the application of tools such as molecular docking and virtual screening, helping researchers understand the mechanism of drug action and design new drugs.

Types and Application Scenarios of Molecular Libraries

1. Bioactive compound library: containing small molecules with known biological activity, used for drug functional repositioning, cell induction, pharmacological research, etc.

2. Natural product compound library: derived from cells, tissues, or secretions of plants, animals, and microorganisms, commonly used for high-throughput screening or computer-aided drug design.

3. The drug diversity compound library contains millions of small molecule compounds, suitable for high-throughput screening and computer virtual screening, and is an effective tool for drug development.

GLPBIO Compound Library Information

1. Product form: Provided in solution form, the solvent is usually DMSO (usually), and water, ethanol, methanol, DMF and other solution forms are also provided according to the solubility characteristics of the compound. The solution concentration is generally 10mM, and a concentration of 2mM、*mg/mL will be provided based on the solubility characteristics of the compound.

2. Product packaging: According to the product quantity and customer requirements, we provide 96 well plates, 96 well deep well plates, and 96 well storage tubes (with QR codes at the bottom) in the form of 80 products per plate.

3. Product specifications: Provide 10μL/well(10mM solution)、20μL/well(10mM solution)、100μL/well(10mM solution) There are three fixed specifications, and other specifications can also be customized according to customer needs.

4. Product information: We provide detailed information for each compound, including the corresponding product for each plate and well, as well as detailed information for each product.

5. Transportation: Dry ice transportation.

GLPBIO Compound Library

1. The FDA Listed Compound Library (GL10001) contains a unique collection of 2819 approved drugs and APIs included in pharmacopoeias, covering fields such as oncology, cardiology, anti-inflammatory, immunology, neuropsychiatrics, and analgesia. It has diverse structures and pharmacological activities, and can be used for high-throughput screening (HTS) and high content screening (HCS).

2. Compound libraries with specific functions, such as Anti cancer Compound Library GL10003 containing 1777 anti-cancer compounds, Neuronal Signaling Library GL10006 containing 948 small molecules related to neural signals, Anti infection Compound Library GL10007 containing 663 small molecules related to infection, Epigenetics Compound Library GL10009 containing 328 small molecules related to epigenetics, Stem Cell Compound Library GL10020 containing 280 small molecules related to stem cells for stem cell research, and Anti dia containing 110 small molecules related to diabetes Betic Compound Library GL10019, etc.

3. Molecular libraries targeting specific signaling pathways, such as those containing 369 tyrosine kinase inhibitors Tyrosine Kinase Inhibitor Library GL10008、 PI3K/Akt/mTOR Compound Library GL10014 containing 178 PI3K/Akt/mTOR inhibitors, JAK/STAT Compound Library GL10021 containing 109 JAK/STAT inhibitors, MAPK Inhibitor Library GL10023 containing 117 MAPK inhibitors, NF - κB Signaling Compound Library GL10024 containing 178 NF - κ inhibitors, TGF beta/Smad Compound Library GL10025 containing 88 TGF - β/Smad inhibitors, etc.