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C18 Phytoceramide (t18:0/18:0) (Synonyms: Cer(t18:0/18:0), Ceramide (t18:0/18:0), N-Octadecanoyl Phytosphingosine, C18:0 Phytoceramide, SPS, N-Stearoyl Phytosphingosine)

Catalog No.GC43052

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S.

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C18 Phytoceramide (t18:0/18:0) Chemical Structure

Cas No.: 34354-88-6

Size Price Stock Qty
5mg
$769.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated murine skin tissue. Formulations containing cer(t18:0/18:0) have been used used in cosmetics as a skin protectants as they reduce water loss to prevent epidermal dehydration and irritation.

Chemical Properties

Cas No. 34354-88-6 SDF
Synonyms Cer(t18:0/18:0), Ceramide (t18:0/18:0), N-Octadecanoyl Phytosphingosine, C18:0 Phytoceramide, SPS, N-Stearoyl Phytosphingosine
Canonical SMILES OC[C@H](NC(CCCCCCCCCCCCCCCCC)=O)[C@@H]([C@@H](CCCCCCCCCCCCCC)O)O
Formula C36H73NO4 M.Wt 584
Solubility Chloroform:Methanol (1:1): Soluble (warmed) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.7123 mL 8.5616 mL 17.1233 mL
5 mM 0.3425 mL 1.7123 mL 3.4247 mL
10 mM 0.1712 mL 0.8562 mL 1.7123 mL
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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