Home>>Lipids>> Sphingolipids>>C6 D-threo Ceramide (d18:1/6:0)

C6 D-threo Ceramide (d18:1/6:0) (Synonyms: N-hexanoyl-D-threo-Sphingosine, D-threo Cer(d18:1/6:0), D-threo Ceramide (d18:1/6:0))

Catalog No.GC40688

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).

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C6 D-threo Ceramide (d18:1/6:0) Chemical Structure

Cas No.: 189894-79-9

Size Price Stock Qty
1mg
$540.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.

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