Cangrelor (sodium salt) (Synonyms: AR-C69931MX) |
| Catalog No.GC43137 |
Cangrelor (sodium salt), an adenosine triphosphate analogue, is a reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects.
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Cas No.: 163706-36-3
Sample solution is provided at 25 µL, 10mM.
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Cangrelor is an ATP analog that inhibits platelet aggregation (IC50 = 0.4 nM). It is a reversible competitive antagonist of the platelet purinergic P2Y12 receptor. Pretreatment with cangrelor significantly reduces blood clotting induced by ADP in a mouse model of pulmonary thromboembolism. Formulations containing cangrelor have been used to prevent blood clotting in at-risk patients.
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