Macrophage Migration Inhibitory Factor
Products for Macrophage Migration Inhibitory Factor
- Cat.No. Product Name Information
- GC48920 β-Carboline-1-carboxylic Acid An alkaloid with diverse biological activities
- GC45270 (±)10(11)-EDP Ethanolamide (±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively).
- GC41648 (±)13(14)-DiHDPA (±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.
- GC41653 (±)16(17)-DiHDPA (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid.
- GC41655 (±)19(20)-EDP Ethanolamide (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).
- GC45266 (+)-Macrosphelide A (+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis.
- GC40444 (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC41220 13(S)-HODE methyl ester 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells.
- GC46733 7,12-Dimethylbenz[a]anthracene 7,12-Dimethylbenz[a]anthracene has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). 7,12-Dimethylbenz[a]anthracene is used to induce tumor formation in various rodent models.
- GC48486 AAA A GPR75 antagonist
- GC46821 Ajoene A disulfide with diverse biological activities
- GC42951 BMP-22 BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM).
- GC42975 BRD32048 ETS variant 1 (ETV1) is a transcription factor oncogene implicated in several cancers where it has been altered by chromosomal translocation, gene amplification, or lineage dysregulation.
- GC48433 BX-320 An inhibitor of PDK1
- GC43042 C17 Lactosylceramide (d18:1/17:0) C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
- GC45403 CAY10735
- GC47098 CL2-SN-38 (dichloroacetic acid salt) An antibody-drug conjugate containing SN-38
- GC43346 Cyclopamine-KAAD Cyclopamine-KAAD, a hedgehog signaling inhibitor, is a smoothened antagonist.
- GC43360 Cytostatin Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice.
- GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice.
- GC45767 Dovitinib-d8 An internal standard for the quantification of dovitinib
- GC45448 Epitalon (acetate)
- GC43719 Fusarisetin A Fusarisetin A is a pentacyclic fungal metabolite first isolated from Fusarium species.
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GC43727
Ganglioside GD1a mixture (sodium salt)
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.
- GC43729 Ganglioside GD3 Mixture (sodium salt) Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.
- GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
- GC47398 Genistein-d4 An internal standard for the quantification of genistein
- GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor
- GC43780 GM 1489 GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively.
- GC48387 Inostamycin A A bacterial metabolite with anticancer activity
- GC47459 Irinotecan-d10 (hydrochloride) An internal standard for the quantification of irinotecan
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GC18909
KRIBB3
KRIBB3 is an Hsp27 and microtubule inhibitor that inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner.
- GC46015 KY 05009 A TNIK inhibitor
- GC47582 Lupulone A beta-acid
- GC48479 Migrastatin A fungal metabolite with antimuscarinic and anticancer activities
- GC44222 ML-298 ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM).
- GC44223 ML-299 ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2 (IC50s = 6 and 20 nM, respectively).
- GC18608 MMP-2/MMP-9 Inhibitor II MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively).
- GC18612 MMP-9/MMP-13 Inhibitor I MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both).
- GC47720 N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine A microbial metabolite with anticancer activity
- GC44313 Naphthofluorescein Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway.
- GC44387 Neurotensin (trifluoroacetate salt) Neurotensin is a neuropeptide that is distributed throughout the CNS and in enteroendocrine cells of the small intestine that has diverse biological activities.
- GC48839 Nifuroxazide-d4 An internal standard for the quantification of nifuroxazide
- GC45760 Nilutamide-d6 An internal standard for the quantification of nilutamide
- GC48788 Norethindrone-d6 An internal standard for the quantification of norethindrone
- GC46018 Norstictic Acid A lichen metabolite
- GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44545 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate.
- GC45777 Peonidin 3-O-glucoside (chloride) An anthocyanin with diverse biological activities
- GC47955 Phloroglucinol A phenol with diverse biological activities
- GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor
- GC47973 PRGL493 An ACSL4 inhibitor
- GC44782 PX-866-17OH A PI3K inhibitor
- GC45554 Questiomycin A
- GC18751 Reticulol Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM).
- GC44847 RKI-1313 A ROCK1 and ROCK2 inhibitor
- GC40285 Rubratoxin A Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM).
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GC40069
Teleocidin A1
Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S.
- GC48659 Umbelliprenin A prenylated coumarin with diverse biological activities
- GC45769 Vandetanib-d6 An internal standard for the quantification of vandetanib