Pyroptosis
Products for Pyroptosis
- Cat.No. Product Name Information
- GA20494 Ac-Asp-Glu-Val-Asp-pNA The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm.
- GC48470 Ac-DEVD-CHO (trifluoroacetate salt) A dual caspase3/caspase7 inhibitor
- GC65107 Ac-FEID-CMK TFA Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor.
- GC60558 Ac-FLTD-CMK Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor.
- GC49704 Ac-FLTD-CMK (trifluoroacetate salt) An inhibitor of caspase-1, -4, -5, and -11
- GC18021 Ac-YVAD-CHO Selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1)
- GC42721 Ac-YVAD-CMK Ac-YVAD-CMK is a selective irreversible inhibitor of caspase-1 (Ki=0.8nM), which can prevent the proinflammatory cytokine IL-1β activation. Ac-YVAD-CMK can reduce the inflammatory response and induce a long-lasting neuroprotective effect.
- GC18421 Dabcyl-YVADAPV-EDANS Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1.
- GC65393 LDC7559 LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages .
- GC49681 Necrosulfonamide-d4 Necrosulfonamide-d4 is the deuterium labeled Necrosulfonamide. Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during the induction of necrosis.
- GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC44967 Suc-YVAD-AMC (acetate) Suc-YVAD-AMC is a fluorogenic substrate for caspase-1.
- GC40151 Z-VAD-AMC (acetate) Z-VAD-AMC is a fluorogenic substrate for caspase-1.