Cefprozil monohydrate |
| Catalog No.GC14460 |
Second-cephalosporin type antibiotic
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 121123-17-9
Sample solution is provided at 25 µL, 10mM.
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Cefprozil monohydrate (BMY-28100) is an orally administered cephalosporin and second-cephalosporin type antibiotic [1].
Cefprozil monohydrate has been reported to resistant to hydrolysis by the beta-lactmases. In addition, Cefprozil monohydrate has been found to be more active than either of the other agents against methicillin-susceptible strains of Staphylococcus aureus and S. epidermidis and all streptococci. For example, the MIC90 values are ≥16μg/ml,1.0μg/ml, 4μg/ml and＞128μg/ml for enterococci, Staphylococcus aureus (methicillin susceptible), Listeria monocytogenes and JK corynebacteria, respectively. Apart from these, Cefprozil monohydrate has been revealed to inhibit both β-lactamase-producing and β-lactamase-negative strains of H. influenzae with the MIC value of ranging from 2 to16μg/ml [1].
References:
[1] Eliopoulos GM, Reiszner E, Wennersten C, Moellering RC Jr. In vitro activity of BMY-28100, a new oral cephalosporin. Antimicrob Agents Chemother. 1987 Apr;31(4):653-6.
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