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Mepivacaine HCl Catalog No.GC10224

local anesthetic

Size Price Stock Qty
10mM (in 1mL DMSO)
In stock
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Animal experiment [1]:

Animal models

Canis familiaris

Dosage form

0.514 and 1.542 mg/kg (intraoral infiltrative administration of 2% mepivacaine HCl with 1:20,000 levonordefrin)


Cardiovascular alterations (increase in the systolic and the mean arterial blood pressures) caused by the administration of 2% mepivacaine HCl with 1:20,000 levonordefrin (Carbocain) in dogs.

Other notes

Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.


[1] Simone JL, Tortamano N, Armonia PL, Rocha RG. Cardiovascular alterations caused by the administration of 2% mepivacaine HCl with 1:20,000 levonordefrin (Carbocain) in dogs. Braz Dent J. 1997;8(2):85-90.

Chemical Properties

Cas No. 1722-62-9 SDF
Synonyms N/A
Chemical Name N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide;hydrochloride
Canonical SMILES CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C.Cl
Formula C15H22N2O.HCl M.Wt 282.81
Solubility ≥ 5.8mg/mL in H2O Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Mepivacaine hydrochloride is a tertiary amine used as a local anesthetic. Target: Sodium Channel Mepivacaine hydrochloride is a local anesthetic of the amide type. Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine hydrochloride is used in any infiltration and regional anesthesia. It is supplied as the hydrochloride salt of the racemate [1]. Mepivacaine hydrochloride displayed a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displayed a preference for TTXs Na(+) channels [2].

[1]. Burm, A.G., et al., Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers. Anesth Analg, 1997. 84(1): p. 85-9.
[2]. Leffler, A., J. Reckzeh, and C. Nau, Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. Eur J Pharmacol, 2010. 630(1-3): p. 19-28.