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Home >> Search results for: 'Ferroptosis'
  1. Cat.No. Product Name Information
  2. GC40193 UAMC-3203 UAMC-3203 is an inhibitor of ferroptosis that has an IC50 value of 10 nM for inhibition of erastin-induced ferroptosis in IMR-32 neuroblastoma cells. UAMC-3203 Chemical Structure
  3. GC10380 Ferrostatin-1 (Fer-1) Ferrostatin-1 (Fer-1) (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1 (Fer-1), a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Antifungal Activity. Ferrostatin-1 (Fer-1) Chemical Structure
  4. GC30039 FIN56

    FIN56, a novel ferroptosis inducer, triggers ferroptosis by increasing the degradation of GPX4 .

     FIN56 Chemical Structure
  5. GC15681 Liproxstatin-1

    Liproxstatin-1 is a potent inhibitor of ferroptosis and can protect against ferroptosis-inducing agents, such as buthionine sulfoxamine (BSO), erastin, and (1S,3R)-RSL3 (RSL3).

     Liproxstatin-1 Chemical Structure
  6. GC52317 BCP-T.A. A ferroptosis inducer BCP-T.A. Chemical Structure
  7. GC63729 GPX4-IN-3 GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM. GPX4-IN-3 Chemical Structure
  8. GC62285 Glutaminase-IN-3 SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM). Glutaminase-IN-3 Chemical Structure
  9. GC61895 Ammonium iron(III) citrate Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production. Ammonium iron(III) citrate Chemical Structure
  10. GC48030 RC574 An inhibitor of ferroptosis RC574 Chemical Structure
  11. GC48029 RC363 An inhibitor of ferroptosis RC363 Chemical Structure
  12. GC50345 Liproxstatin-1 hydrochloride Potent ferroptosis inhibitor Liproxstatin-1 hydrochloride Chemical Structure
  13. GC45793 IM-93 A dual inhibitor of ferroptosis and NETosis IM-93 Chemical Structure
  14. GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) An inducer of ferroptosis Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Chemical Structure
  15. GC45248 (-)-FINO2 (-)-FINO2 is a ferroptosis-inducing peroxide compound that indirectly inhibits glutathione peroxidase 4 (GPX4) and oxidizes iron. (-)-FINO2 Chemical Structure
  16. GC44947 SRS16-86 A ferroptosis inhibitor SRS16-86 Chemical Structure
  17. GC43623 Erastin2 A ferroptosis inducer Erastin2 Chemical Structure
  18. GC42928 BHT BHT is an antioxidant widely used in foods and in food-related products. BHT is a Ferroptosis inhibitor. BHT Chemical Structure
  19. GC40922 SRS11-92 SRS11-92 is a ferroptosis inhibitor and a derivative of ferrostatin-1. SRS11-92 Chemical Structure
  20. GC34939 UAMC-3203 hydrochloride A ferroptosis inhibitor UAMC-3203 hydrochloride Chemical Structure
  21. GC40211 Ferrostatin-1 Diyne Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1. Ferrostatin-1 Diyne Chemical Structure
  22. GC30512 Vatiquinone (EPI-743) Vatiquinone (EPI-743) (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. Vatiquinone (EPI-743) Chemical Structure
  23. GC16630 Erastin

    Erastin is a cell-permeable ferroptosis activatior and antitumor agent.

     Erastin Chemical Structure

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  1. Signaling Pathways22
    1. ....Proteases4
      1. ........Glutaminase1
      2. ........Glutathione Peroxidase1
      3. ........Mitochondrial Metabolism2
    2. ....Metabolism20
      1. ........Ferroptosis20
      2. ........Necrosis1
    3. ....Cell Cycle/Checkpoint1
      1. ........ECM & Adhesion Molecules1
    4. ....Membrane Transporter/Ion Channel1
    5. ....Neuroscience4
      1. ........Huntington1
      2. ........Neuroprotection2
    6. ....Immunology/Inflammation6
      1. ........Reactive Oxygen Species5
      2. ........Glutathione1
      3. ........Innate Immunity2
    7. ....Ox Stress Reagents7
      1. ........Antioxidants3
      2. ........Lipid Peroxidation4
      3. ........Pro-Oxidant Activity3
    8. ....Others1
      1. ........MDR multidrug resistance1
  2. Infectious Disease1