CAY10726 |
| Catalog No.GC43203 |
CAY10726 is an arylurea fatty acid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1611446-66-2
Sample solution is provided at 25 µL, 10mM.
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CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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