Ceapin-A7 |
| Catalog No.GC61606 |
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2323027-38-7
Sample solution is provided at 25 µL, 10mM.
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Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings[1].
Ceapin-A7 sensitizes cells to ER stress[1].Ceapin (0.6-18.9 μM; 4.5 hours) selectively inhibits ATF6α but not ATF6β[1].
[1]. Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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