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Cefadroxil-d4 (trifluoroacetate salt)

Catalog No.GC48489

An internal standard for the quantification of cefadroxil

Products are for research use only. Not for human use. We do not sell to patients.

Cefadroxil-d4 (trifluoroacetate salt) Chemical Structure

Cas No.: 1426215-61-3

Size Price Stock Qty
500µg
$170.00
In stock
1mg
$321.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Cefadroxil-d4 is intended for use as an internal standard for the quantification of cefadroxil by GC- or LC-MS. Cefadroxil is a semisynthetic cephalosporin antibiotic.1 It is active against a variety of Gram-positive and Gram-negative bacteria, including B. anthracis, V. cholerae, and P. multocida strains (MICs = 1, 2, and 4 µg/ml, respectively), among others. Cefadroxil is protective against infection by strains of S. pyogenes, S. pneumoniae, or S. aureus in mice with 50% protective dose (PD50) values of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.

1.Buck, R.E., and Price, K.E.Cefadroxil, a new broad-spectrum cephalosporinAntimicrob. Agents Chemother.11(2)324-330(1977)

Chemical Properties

Cas No. 1426215-61-3 SDF
Canonical SMILES OC1=C([2H])C([2H])=C([C@@H](N)C(N[C@@H]2C(N3[C@]2([H])SCC(C)=C3C(O)=O)=O)=O)C([2H])=C1[2H].OC(C(F)(F)F)=O
Formula C16H13D4N3O5S•CF3COOH M.Wt 481.4
Solubility DMSO: soluble,Methanol: soluble,Water: soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0773 mL 10.3864 mL 20.7727 mL
5 mM 0.4155 mL 2.0773 mL 4.1545 mL
10 mM 0.2077 mL 1.0386 mL 2.0773 mL
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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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