Chlormethiazole hydrochloride (Synonyms: Clomethiazole) |
| Catalog No.GC16311 |
GABAA agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6001-74-7
Sample solution is provided at 25 µL, 10mM.
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Clomethiazole hydrochloride is a sedative and anticonvulsant. Clomethiazole hydrochloride is neuroprotective and prevents the degeneration of serotonergic nerve terminals induced by 3,4-methylenedioxymethamphetamine (MDMA)[1][2].
References:
[1]. Hewitt KE, et al. Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats. Neuropharmacology. 1994 Dec;33(12):1589-95.
[2]. Cross AJ, et al. The protective action of chlormethiazole against ischaemia-induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity. Br J Pharmacol. 1995 Apr;114(8):1625-30.
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