(+)-Cloprostenol isopropyl ester (Synonyms: (+)-5-cis Cloprostenol isopropyl ester, (+)16mchlorophenoxy tetranor Prostaglandin F2α isopropyl ester) |
| Catalog No.GC45260 |
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 157283-66-4
Sample solution is provided at 25 µL, 10mM.
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(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α. (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M. (+)-Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.
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