CRBN-6-5-5-VHL |
| Catalog No.GC50619 |
Potent and selective cereblon degrader; cell-permeable
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2362575-45-7
Sample solution is provided at 25 µL, 10mM.
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Potent and selective cereblon degrader (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable.
Steinebach et al (2019) PROTAC-mediated crosstalk between E3 ligases. Chem.Commun.(Camb) 55 1821 PMID:30672516
Review for CRBN-6-5-5-VHL
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
Review for CRBN-6-5-5-VHL
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