CVT-11127 (Synonyms: GS-456332) |
| Catalog No.GC66005 |
CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1018674-83-3
Sample solution is provided at 25 µL, 10mM.
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CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1].
CVT-11127 (1 µM, 48 h) shows antiproliferation activity in H460 cells[1].
CVT-11127 (1 µM, 48 h) decreases the the population of cells in S-phase by 75%[1].
CVT-11127 (1 µM, 48 h) induces apoposis in H460 cells[1].
CVT-11127 (1, 2 µM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells[1].
Cell Proliferation Assay[1]
| Cell Line: | H460 cells |
| Concentration: | 1 µM |
| Incubation Time: | 48 h |
| Result: | Showed antiproliferation activity. |
Cell Cycle Analysis[1]
| Cell Line: | H460 cells |
| Concentration: | 1 µM |
| Incubation Time: | 48 h |
| Result: | Decreased the the population of cells in S-phase by 75%. |
Apoptosis Analysis[1]
| Cell Line: | H460 cells |
| Concentration: | 1 µM |
| Incubation Time: | 24 h |
| Result: | Induced apoposis H460 cells. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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