Cyclo(L-Trp-L-Trp) (Synonyms: Cyclic dioxopiperazine-L-tryptophan-L-tryptophan) |
Catalog No.GC18268 |
Cyclo(L-Trp-L-Trp) is a cyclic dipeptide that has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines.
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Cas No.: 20829-55-4
Sample solution is provided at 25 µL, 10mM.
Cyclo(L-Trp-L-Trp) is a cyclic dipeptide that has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines. It has antibacterial activity and inhibits growth of 41 out of 49 strains of multidrug resistant A. baumannii (MICs = 12.5-25 ug/ml) as well as B. subtilis, M. luteus, S. aureus, S. cerevisiae, A. niger, and C. albicans (MICs = 12.5-50 ug/ml). Prenylated forms of cyclo(L-Trp-L-Trp) are cytotoxic against human leukemia and ovarian cell lines.
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