Home>>D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt)

D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) (Synonyms: Ins(3,4,5,6)P4, 3,4,5,6IP4)

Catalog No.GC43536

D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) (Ins(3,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction.

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D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) Chemical Structure

Size Price Stock Qty
100μg
$188.00
In stock
500μg
$848.00
In stock
1mg
$1,508.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Background

D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) (Ins(3,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. It almost completely inhibits calcium-activated chloride channels at a concentration of 8-10 µM. Related inositol oligophosphates Ins(1,3,4,5)-P4, Ins(1,3,4,6)-P4, Ins(1,4,5,6)-P4, and Ins(1,3,4,5,6)-P5 do not inhibit the calcium channel at concentrations up to 100 µM. Ins(1,3,4)P3-mediated inhibition of Ins(3,4,5,6)-P4 1-kinase increases the cellular level of Ins(3,4,5,6)-P4, thus regulating channel inhibition. Ins(3,4,5,6)-P4 was found to be inactive when analyzed for Ca2+-releasing potency in Xenopus oocytes.

Chemical Properties

Cas No. SDF
Synonyms Ins(3,4,5,6)P4, 3,4,5,6IP4
Canonical SMILES O[C@H]1[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H]1O.[Na+].[Na+].[Na+].[Na+]
Formula C6H12O18P4•4Na M.Wt 588
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.7007 mL 8.5034 mL 17.0068 mL
5 mM 0.3401 mL 1.7007 mL 3.4014 mL
10 mM 0.1701 mL 0.8503 mL 1.7007 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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