1-Alaninechlamydocin |
Katalog-Nr.GC41984 |
1-Alaninechlamydocin, ein zyklisches Tetrapeptid, ist ein potenter HDAC-Inhibitor (IC50 = 6,4 nM). 1-Alaninechlamydocin induziert G2/M-Zellzyklusarrest und Apoptose in MIA-PaCa-2-Zellen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 141446-96-0
Sample solution is provided at 25 µL, 10mM.
1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
Average Rating: 5
(Based on Reviews and 38 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *