1-Palmitoyl-2-hydroxy-sn-glycero-3-PC (Synonyms: 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine, Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 16:0/0:0-PC) |
| Katalog-Nr.GC42026 |
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ist ein hÄufig vorkommendes Gonaden-LPC (Lysophosphatidylcholin).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 17364-16-8
Sample solution is provided at 25 µL, 10mM.
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. The hydrolysis of phospholipids by arachidonoyl-selective PLA2s is the initiating event in many eicosanoid-based signal transduction pathways. Many other reactions also generate phosphatidylcholine species with a free hydroxyl group in the sn-2 position. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC augments inflammation through effects on adhesion molecules and growth factors, monocytes, and macrophages. The lymphocyte G protein-coupled receptor G2A binds 1-palmitoyl-2-hydroxy-sn-glycero-3-PC as a specific ligand with a Kd of 65 nM; this receptor also binds the related phospholipid sphingosyl phosphorylcholine.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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