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12-O-Methylcarnosic acid (Synonyms: Carnosic acid 12-methyl ether, 12-Methoxycarnosic Acid)

Katalog-Nr.GC64008

12-O-MethylcarnosinsÄure (12-MethoxycarnosinsÄure), eine aus dem Acetonextrakt von Salvia microphylla isolierte DiterpencarnosinsÄure, ist ein aktiver Bestandteil der 5α-Reduktase-Hemmung mit einem IC50-Wert von 61,7 μM.

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12-O-Methylcarnosic acid Chemische Struktur

Cas No.: 62201-71-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity[1][2].

12-O-Methylcarnosic acid (12-Methoxycarnosic acid; 5 μM) inhibits androgen-dependent proliferation of LNCaP cells as 66.7%[1]. 12-O-Methylcarnosic acid shows antimicrobial activity against S. aureus at 78 μg/mL[2].

[1]. Kazuya Murata, et al. Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract. Phytother Res. 2013 Feb;27(2):212-7.
[2]. Zeynep Aydogmu?, et al. Constituents of Salvia Microphylla. Nat Prod Res. 2006 Jul 10;20(8):775-81.

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