(±)-Clopidogrel (hydrochloride) |
| Katalog-Nr.GC41668 |
Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130209-90-4
Sample solution is provided at 25 µL, 10mM.
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Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix®, clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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