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2'-Deoxy-5'-O-DMT-2'-fluorouridine

Katalog-Nr.GC67627

2&7#39;-Deoxy-5'-O-DMT-2'-Fluoruridin, ein Nukleosid-Analogon, ist ein 5&7#39;-O-DMTr-5-FUDR-Derivat mit starker Aktivität gegen Gelbfieber (YFV).

Products are for research use only. Not for human use. We do not sell to patients.

2'-Deoxy-5'-O-DMT-2'-fluorouridine Chemische Struktur

Cas No.: 146954-74-7

Größe Preis Lagerbestand Menge
5g
329,00 $
Auf Lager
25g
1.153,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity[1].

2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1].

[1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35.

Chemical Properties

Cas No. 146954-74-7 SDF Download SDF
Formula C30H29FN2O7 M.Wt 548.56
Löslichkeit Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.823 mL 9.1148 mL 18.2295 mL
5 mM 0.3646 mL 1.823 mL 3.6459 mL
10 mM 0.1823 mL 0.9115 mL 1.823 mL
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Gewicht
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Konzentration
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Inhalt
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**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

Berechnen

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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