2'-O-Methylguanosine |
| Katalog-Nr.GC41612 |
2'-O-Methylguanosin ist ein modifiziertes Nukleosid, das in tRNAs durch die Wirkung von tRNA Guanosin-2'-O-Methyltransferase produziert wird.
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Cas No.: 2140-71-8
Sample solution is provided at 25 µL, 10mM.
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2'-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA. 2'-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2'-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.
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