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(2'S)-Nicotine-1-oxide (Synonyms: Nicotine-N-oxide)

Katalog-Nr.GC18622

(2'S)-Nicotine-1-oxide is a metabolite of nicotine .

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(2'S)-Nicotine-1-oxide Chemische Struktur

Cas No.: 2820-55-5

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1mg
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5mg
226,00 $
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10mg
398,00 $
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25mg
872,00 $
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Sample solution is provided at 25 µL, 10mM.

Description of (2'S)-Nicotine-1-oxide

(2'S)-Nicotine-1-oxide is a metabolite of nicotine . It is formed when nicotine is metabolized in the liver by cytochrome P450 (CYP) isoform CYP2A6. (2'S)-Nicotine-1-oxide has been detected in human sperm and semen.

Chemical Properties of (2'S)-Nicotine-1-oxide

Cas No. 2820-55-5 SDF
Überlieferungen Nicotine-N-oxide
Chemical Name 3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine 1-oxide
Canonical SMILES CN1CCC[C@H]1C2=C[N+]([O-])=CC=C2
Formula C10H14N2O M.Wt 178.2
Löslichkeit DMF: 50 mg/mL,DMSO: 30 mg/mL,Ethanol: 50 mg/mL,PBS (pH 7.2): 1 mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (2'S)-Nicotine-1-oxide

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.6117 mL 28.0584 mL 56.1167 mL
5 mM 1.1223 mL 5.6117 mL 11.2233 mL
10 mM 0.5612 mL 2.8058 mL 5.6117 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of (2'S)-Nicotine-1-oxide

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for (2'S)-Nicotine-1-oxide

Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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