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20S Proteasome-IN-1

Katalog-Nr.GC64472

20S Proteasom-IN-1 ist ein 26S-Proteasom-Inhibitor, der aus dem Patent WO2006128196A2 Verbindung 2 extrahiert wurde.

Products are for research use only. Not for human use. We do not sell to patients.

20S Proteasome-IN-1 Chemische Struktur

Cas No.: 858557-69-4

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5 mg
135,00 $
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10 mg
216,00 $
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25 mg
405,00 $
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50 mg
603,00 $
Auf Lager
100 mg
882,00 $
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

20S Proteasome-IN-1 is a 26S proteasome inhibitor extracted from patent WO2006128196A2 compound 2. 20S Proteasome-IN-1 has the potential for cancer, immune-related disorders, inflammation, ischemic conditions, neurodegenerative disorders and other diseases research[1].

[1]. Parlati F, et, al. Novel substrate for rpn 11 enzymatic activity. WO2006128196A2.

Chemical Properties

Cas No. 858557-69-4 SDF Download SDF
Formula C23H25N3O4 M.Wt 407.46
Löslichkeit DMSO : 31.25 mg/mL (76.69 mM; ultrasonic and warming and heat to 60°C) Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4542 mL 12.2711 mL 24.5423 mL
5 mM 0.4908 mL 2.4542 mL 4.9085 mL
10 mM 0.2454 mL 1.2271 mL 2.4542 mL
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Gewicht
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Konzentration
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Inhalt
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MW*
 
 
 
**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

Berechnen

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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