25D-NBOMe (hydrochloride) (Synonyms: 2C-D-NBOMe) |
| Katalog-Nr.GC42097 |
2C-D, a 2,5-dimethoxy phenethylamine, is designer drug with mild hallucinogenic activity, due in part to weak activity at serotonin receptors.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1539266-35-7
Sample solution is provided at 25 µL, 10mM.
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2C-D , a 2,5-dimethoxy phenethylamine, is designer drug with mild hallucinogenic activity, due in part to weak activity at serotonin receptors. [1][2] 25D-NBOMe is a derivative of 2C-D, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.[3][4] This product is intended for research and forensic applications.
Reference:
[1]. Meyer, M.R., and Maurer, H.H. Metabolism of designer drugs of abuse: An updated review. Curr. Drug Metab. 11(5), 468-482 (2010).
[2]. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. Journal of Pharmacology and Experimental Therapeutics 321, 1054-1061 (2007).
[3]. Braden, M.R., Parrish, J.C., Naylor, J.C., et al. Molecular interaction of serotonin 5-HT2A receptor residues Phe3396.51 and Phe3406.52 with superpotent N-benzyl phenethylamine agonists. Mol. Pharm. 70(6), 1956-1965 (2006).
[4]. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J.Nuclear Med. 51(11), 1763-1770 (2010).
| Cas No. | 1539266-35-7 | SDF | |
| Überlieferungen | 2C-D-NBOMe | ||
| Chemical Name | 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine, monohydrochloride | ||
| Canonical SMILES | CC1=C(OC)C=C(CCNCC2=C(OC)C=CC=C2)C(OC)=C1.Cl | ||
| Formula | C19H25NO3•HCl | M.Wt | 351.9 |
| Löslichkeit | 5mg/mL in DMSO, 3mg/mL in DMF, 13mg/mL in Ethanol | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.8417 mL | 14.2086 mL | 28.4172 mL |
| 5 mM | 568.3 μL | 2.8417 mL | 5.6834 mL |
| 10 mM | 284.2 μL | 1.4209 mL | 2.8417 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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