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3-O-Methylgallic acid

Katalog-Nr.GC60507

3-O-MethylgallussÄure (3,4-Dihydroxy-5-methoxybenzoesÄure) ist ein Anthocyanin-Metabolit und hat eine starke antioxidative Wirkung. 3-O-MethylgallussÄure hemmt die Caco-2-Zellproliferation mit einem IC50-Wert von 24,1 μM. 3-O-MethylgallussÄure induziert auch Zellapoptose und hat Anti-Krebs-Wirkungen.

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3-O-Methylgallic acid Chemische Struktur

Cas No.: 3934-84-7

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500mg
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

[1]. Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7. [2]. Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.

Chemical Properties

Cas No. 3934-84-7 SDF
Canonical SMILES O=C(O)C1=CC(OC)=C(O)C(O)=C1
Formula C8H8O5 M.Wt 184.15
Löslichkeit DMSO: 50 mg/mL (271.52 mM); Water: 2.2 mg/mL (11.95 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 5.4304 mL 27.1518 mL 54.3036 mL
5 mM 1.0861 mL 5.4304 mL 10.8607 mL
10 mM 0.543 mL 2.7152 mL 5.4304 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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