5-OMe-UTP,100mM Sodium Solution |
Katalog-Nr.GB20004 |
5-OMe-UTP is a methoxy-modified UTP analog commonly used to replace naturally occurring UTP during in vitro mRNA synthesis.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
-
Purity: ≥98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
5-Methoxyuridine-5'-Triphosphate (5-OMe-UTP) is a methoxy-modified UTP analogue of naturally occurring uridine triphosphate (UTP) [1]. 5-OMe-UTP is also a common chemical modification used in in vitro mRNA synthesis for incorporation into messenger RNA (mRNA) using T7 RNA polymerase, thereby reducing the activity and immunogenicity of the resulting mRNA[2].
References:
[1]. Denzil Furtado, Christina Cortez-Jugo, et al. "mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts." Mol Pharm. PMID: 36125338
[2]. Li, Bin; Zeng, Chunxi; Dong, Yizhou . Design and assessment of engineered CRISPR-Cpf1 and its use for genome editing.
Cas No. | SDF | ||
Formula | C10H14N2Na3O16P3 | M.Wt | 580.11 |
Löslichkeit | Storage | Store at -20°C or below, always avoid freeze-thaw cycles. | |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 1.7238 mL | 8.6191 mL | 17.2381 mL |
5 mM | 0.3448 mL | 1.7238 mL | 3.4476 mL |
10 mM | 0.1724 mL | 0.8619 mL | 1.7238 mL |
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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