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5-OMe-UTP,100mM Sodium Solution

Katalog-Nr.GB20004

5-OMe-UTP is a methoxy-modified UTP analog commonly used to replace naturally occurring UTP during in vitro mRNA synthesis.

Products are for research use only. Not for human use. We do not sell to patients.

5-OMe-UTP,100mM Sodium Solution Chemische Struktur

Größe Preis Lagerbestand Menge
500μL
990,00 $
Auf Lager
100μL
330,00 $
Auf Lager
1mL
1.600,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

5-Methoxyuridine-5'-Triphosphate (5-OMe-UTP) is a methoxy-modified UTP analogue of naturally occurring uridine triphosphate (UTP) [1]. 5-OMe-UTP is also a common chemical modification used in in vitro mRNA synthesis for incorporation into messenger RNA (mRNA) using T7 RNA polymerase, thereby reducing the activity and immunogenicity of the resulting mRNA[2].

References:
[1]. Denzil Furtado, Christina Cortez-Jugo, et al. "mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts." Mol Pharm. PMID: 36125338
[2]. Li, Bin; Zeng, Chunxi; Dong, Yizhou . Design and assessment of engineered CRISPR-Cpf1 and its use for genome editing.

Chemical Properties

Cas No. SDF
Formula C10H14N2Na3O16P3 M.Wt 580.11
Löslichkeit Storage Store at -20°C or below, always avoid freeze-thaw cycles.
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7238 mL 8.6191 mL 17.2381 mL
5 mM 0.3448 mL 1.7238 mL 3.4476 mL
10 mM 0.1724 mL 0.8619 mL 1.7238 mL
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**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

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