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β-D-Glucose (Synonyms: NSC 287045)

Katalog-Nr.GC40777

D-Glucose, a naturally occurring monosaccharide found in plants, is the primary energy source for living organisms.

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β-D-Glucose Chemische Struktur

Cas No.: 492-61-5

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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Background

D-Glucose, a naturally occurring monosaccharide found in plants, is the primary energy source for living organisms.[1] It is utilized as a metabolic intermediate by cells for either aerobic or anaerobic respiration. D-Glucose exists in two cyclic forms, α-D-glucose and β-D-glucose, based on the position of the substituent at the anomeric center.[2] α-D-Glucose is the monomer unit in starch, whereas β-D-glucose is the monomer unit in cellulose.2 When one of these anomers is added to solution, it undergoes reversible epimerization to the other via an open-chain form, during which the specific rotation of the solution changes gradually until it reaches equilibrium. The existence of multiple binding modes of this single monosaccharide has been studied as a model scaffold to design compounds with increased probability of ligand binding.[3]

Reference:
[1]. Slein, M.W. D-glucose, determination with hexokinase and glucose-6-phosphate dehydrrogenase. Methods of Enzymatic Analysis 1, 117-123 (1963).
[2]. Horton, H.R. Carbohydrates. Principles of biochemistry 9, 16-22 (1993).
[3]. Hirschmann, R.F., Nicolaou, K.C., Angeles, A.R., et al. The β-D-glucose scaffold as a β-turn mimetic. Accounts of Chemical Research 42(10), 1511-1520 (2009).

Chemical Properties

Cas No. 492-61-5 SDF
Überlieferungen NSC 287045
Canonical SMILES O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Formula C6H12O6 M.Wt 180.2
Löslichkeit 20mg/mL in DMSO, 10mg/mL in DMF, PBS (pH 7.2): 10 mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.5494 mL 27.7469 mL 55.4939 mL
5 mM 1.1099 mL 5.5494 mL 11.0988 mL
10 mM 0.5549 mL 2.7747 mL 5.5494 mL
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**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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