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β-D-glucuronide-pNP-carbonate

Katalog-Nr.GC66750

β-D-Glucuronid-pNP-Carbonat ist ein spaltbarer ADC-Linker, der bei der Synthese von Antikörper-Wirkstoff-Konjugaten (ADCs) verwendet wird.

Products are for research use only. Not for human use. We do not sell to patients.

β-D-glucuronide-pNP-carbonate Chemische Struktur

Cas No.: 894095-98-8

Größe Preis Lagerbestand Menge
100mg
494,00 $
Auf Lager
250mg
987,00 $
Auf Lager
500mg
1.481,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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