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Articaine HCl (Synonyms: Carticaine, HOE 045, HOE 40045)

Katalog-Nr.GC13404

Articain HCl (Hoe-045) ist ein Amid-AnÄsthetikum, das eine Estergruppe enthÄlt, die reversibel an die ⋱-Untereinheit der spannungsgesteuerten NatriumkanÄle in der inneren KavitÄt des Nervs bindet und eine wirksame Schmerzlinderung bieten kann.

Products are for research use only. Not for human use. We do not sell to patients.

Articaine HCl Chemische Struktur

Cas No.: 23964-57-0

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10mM (in 1mL DMSO)
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50mg
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Sample solution is provided at 25 µL, 10mM.

Description of Articaine HCl

Articaine (hydrochloride) (Hoe-045) is a dental local anesthetic.

References:
[1]. Malamed, S.F., S. Gagnon, and D. Leblanc, A comparison between articaine HCl and lidocaine HCl in pediatric dental patients. Pediatr Dent, 2000. 22(4): p. 307-11.

Chemical Properties of Articaine HCl

Cas No. 23964-57-0 SDF
Überlieferungen Carticaine, HOE 045, HOE 40045
Chemical Name methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate;hydrochloride
Canonical SMILES CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl
Formula C13H20N2O3S.HCl M.Wt 320.84
Löslichkeit ≥ 13.35mg/mL in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Articaine HCl

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.1168 mL 15.5841 mL 31.1682 mL
5 mM 623.4 μL 3.1168 mL 6.2336 mL
10 mM 311.7 μL 1.5584 mL 3.1168 mL
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In vivo Formulation Calculator (Clear solution) of Articaine HCl

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 12 reference(s) in Google Scholar.)

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