B-Raf IN 1 (Synonyms: B-RAF Inhibitor 1) |
Katalog-Nr.GC10534 |
B-Raf IN 1 ist ein potenter und selektiver B-Raf-Kinase-Inhibitor mit einem IC50 von 24 nM.
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Cas No.: 950736-05-7
Sample solution is provided at 25 µL, 10mM.
B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.
B-Raf IN 1 (Compound 10n) inhibits WM 266-4 and HT29 cells with IC50s of 0.92 and 0.78 μM, respectively[1].
References:
[1]. Berger DM, et al. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23.
Average Rating: 5
(Based on Reviews and 22 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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