BMP2-derived Peptide (trifluoroacetate salt) (Synonyms: Bone Morphogenic Protein 2-derived Peptide, KIPKASSVPTELSAISTLYL-NH2) |
| Katalog-Nr.GC52376 |
A synthetic peptide
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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BMP2-derived peptide is a synthetic peptide that corresponds to residues 73-92 of bone morphogenetic protein 2 (BMP2) and has a role in osteogenesis.1 It increases alkaline phosphatase (ALP) activity in C3H/10T1/2 murine mesenchymal cells when used at concentrations of 100 and 200 µg/well. BMP2-derived peptide (100 µg/well) increases mRNA expression of the gene encoding osteocalcin in C3H/10T1/2 cells. It induces osteoblast-like cell differentiation and ectopic calcification when conjugated to an alginate gel in rats when administered via a submuscular implant.2
1.Saito, A., Suzuki, Y., Ogata, S.I., et al.Activation of osteo-progenitor cells by a novel synthetic peptide derived from the bone morphogenetic protein-2 knuckle epitopeBiochim. Biophys. Acta1651(1-2)60-67(2003) 2.Saito, A., Suzuki, Y., Ogata, S.-I., et al.Prolonged ectopic calcification induced by BMP-2-derived synthetic peptideJ. Biomed. Mater. Res. A70(1)115-121(2004)
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