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α-D-Glucose-1,6-bisphosphate (potassium salt hydrate) (Synonyms: D-Glucose-1,6-diphosphate)

Katalog-Nr.GC48278

A bis-phosphorylated derivative of α-D-glucose

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α-D-Glucose-1,6-bisphosphate (potassium salt hydrate) Chemische Struktur

Cas No.: 91183-87-8

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

α-D-Glucose-1,6-bisphosphate is a bis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1 It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2 It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4 α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism.

1.Beitner, R.Regulation of carbohydrate metabolism by glucose 1,6-bisphosphate in extrahepatic tissues; comparison with fructose 2,6-bisphosphateInt. J. Biochem.22(6)553-557(1990) 2.Maliekal, P., Sokolova, T., Vertommen, D., et al.Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the α-D-phosphohexomutase familyJ. Biol. Chem.282(44)31844-31851(2007) 3.Moustafa, H.M.A., Zaghloul, T.I., and Zhang, Y.-H.P.A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritimaAnal. Biochem.50175-81(2016) 4.Panosian, T.D., Nannemann, D.P., Watkins, G.R., et al.Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycleJ. Biol. Chem.286(10)8043-8054(2011)

Chemical Properties

Cas No. 91183-87-8 SDF
Überlieferungen D-Glucose-1,6-diphosphate
Canonical SMILES [O-]P(OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OP([O-])([O-])=O)O1)([O-])=O.[K+].[K+].[K+].[K+].O
Formula C6H10O12P2.4K [XH2O] M.Wt 492.5
Löslichkeit Water: 50 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0305 mL 10.1523 mL 20.3046 mL
5 mM 0.4061 mL 2.0305 mL 4.0609 mL
10 mM 0.203 mL 1.0152 mL 2.0305 mL
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