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11β-Hydroxyetiocholanolone (Synonyms: NSC 53897)

Katalog-Nr.GC48787

A metabolite of hydrocortisone

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11β-Hydroxyetiocholanolone Chemische Struktur

Cas No.: 739-26-4

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

11β-Hydroxyetiocholanolone is a metabolite of hydrocortisone .1 Fecal levels of 11β-hydroxyetiocholanolone are increased in response to environmental stress in giraffes (G. camelopardalis) and plains zebras (E. quagga).2,3

1.Shackleton, C.H.L., Neres, M.S., Hughes, B.A., et al.17-Hydroxylase/C17,20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolitesSteroids73(6)652-656(2008) 2.Bashaw, M.J., Sicks, F., Palme, R., et al.Non-invasive assessment of adrenocortical activity as a measure of stress in giraffe (Giraffa camelopardalis)BMC Vet. Res.12(1)235(2016) 3.Seeber, P.A., Franz, M., Dehnhard, M., et al.Plains zebra (Equus quagga) adrenocortical activity increases during times of large aggregations in the Serengeti ecosystemHorm. Behav.1021-9(2018)

Chemical Properties

Cas No. 739-26-4 SDF
Überlieferungen NSC 53897
Canonical SMILES C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](CC2)O)([H])[C@@]4([H])[C@](C[C@@H]3O)(C(CC4)=O)C
Formula C19H30O3 M.Wt 306.4
Löslichkeit Methanol: soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.2637 mL 16.3185 mL 32.6371 mL
5 mM 0.6527 mL 3.2637 mL 6.5274 mL
10 mM 0.3264 mL 1.6319 mL 3.2637 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Average Rating: 5 ★★★★★ (Based on Reviews and 19 reference(s) in Google Scholar.)

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