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(+)-Cloprostenol (sodium salt) (Synonyms: DCloprostenol, (+)16mchlorophenoxy tetranor PGF2α, (+)16mchlorophenoxy tetranor Prostaglandin F2α)

Katalog-Nr.GC45259

(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.

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(+)-Cloprostenol (sodium salt) Chemische Struktur

Cas No.: 62561-03-9

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol. (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. Cloprostenol is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively without the side effects associated with PGF2α. The subcutaneous dose required for interrupting early pregnancy is species dependent, requiring approximately 1.25 µg/kg and 270 µg/kg in hamsters and rats, respectively. Cloprostenol is also a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3 x 10-12 M.

Chemical Properties

Cas No. 62561-03-9 SDF
Überlieferungen DCloprostenol, (+)16mchlorophenoxy tetranor PGF2α, (+)16mchlorophenoxy tetranor Prostaglandin F2α
Canonical SMILES O[C@@H]1[C@H](C/C=C\CCCC([O-])=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(Cl)=C2)[C@H](O)C1.[Na+]
Formula C22H28ClO6•Na M.Wt 446.9
Löslichkeit DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.2376 mL 11.1882 mL 22.3764 mL
5 mM 0.4475 mL 2.2376 mL 4.4753 mL
10 mM 0.2238 mL 1.1188 mL 2.2376 mL
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