(E/Z)-Zotiraciclib hydrochloride (Synonyms: (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride) |
Katalog-Nr.GC63864 |
(E/Z)-Zotiraciclib ((E/Z)-TG02)-Hydrochlorid ist ein potenter CDK2-, JAK2- und FLT3-Inhibitor.
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Cas No.: 1321626-25-8
Sample solution is provided at 25 µL, 10mM.
(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent CDK2, JAK2, and FLT3 inhibitor[1].
[1]. William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer. J Med Chem. 2012;55(1):169-196.
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