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(+)-Talarozole

Katalog-Nr.GC34960

(+)-Talarozol ist ein potenter Inhibitor des RetinsÄurestoffwechsels, extrahiert aus dem Patent WO 1997049704 A1.

Products are for research use only. Not for human use. We do not sell to patients.

(+)-Talarozole Chemische Struktur

Cas No.: 201410-66-4

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10mM (in 1mL DMSO)
301,00 $
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1mg
176,00 $
Auf Lager
5mg
362,00 $
Auf Lager
10mg
603,00 $
Auf Lager
25mg
1.391,00 $
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50mg
2.225,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description of (+)-Talarozole

(+)-Talarozole is a potent inhibitor of retinoic acid metabolism extracted from patent WO 1997049704 A1. retinoic acid[1]

[1]. Marc Gaston Venet, et al. N-[4-(heteroarylmethyl)phenyl]-heteroarylamines. WO 1997049704 A1.

Chemical Properties of (+)-Talarozole

Cas No. 201410-66-4 SDF
Canonical SMILES CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4.[(+)].[Rotation]
Formula C21H23N5S M.Wt 377.51
Löslichkeit DMSO: ≥ 72 mg/mL (190.72 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (+)-Talarozole

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6489 mL 13.2447 mL 26.4894 mL
5 mM 0.5298 mL 2.6489 mL 5.2979 mL
10 mM 0.2649 mL 1.3245 mL 2.6489 mL
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In vivo Formulation Calculator (Clear solution) of (+)-Talarozole

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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