(2S)-2'-Methoxykurarinone (Synonyms: 2'-O-Methylkurarinone) |
Katalog-Nr.GC34970 |
(2S)-2'-Methoxykurarinon, eine aus den Wurzeln von Sophora flavescens isolierte Verbindung, hat entzÜndungshemmende, fiebersenkende, antidiabetische und antineoplastische Wirkungen.
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Cas No.: 270249-38-2
Sample solution is provided at 25 µL, 10mM.
(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells[1][2].
[1]. Kim JY, et al. (2S)-2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. Biol Pharm Bull. 2014;37(2):255-61. [2]. Kang TH, et al. Cytotoxic lavandulyl flavanones from Sophora flavescens. J Nat Prod. 2000 May;63(5):680-1.
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